TY - GEN AU - Chen,Zhen AU - Wen,Liang AU - Martin,Marcy AU - Hsu,Chien-Yi AU - Fang,Longhou AU - Lin,Feng-Mao AU - Lin,Ting-Yang AU - Geary,McKenna J AU - Geary,Greg G AU - Zhao,Yongli AU - Johnson,David A AU - Chen,Jaw-Wen AU - Lin,Shing-Jong AU - Chien,Shu AU - Huang,Hsien-Da AU - Miller,Yury I AU - Huang,Po-Hsun AU - Shyy,John Y-J TI - Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a SN - 1524-4539 PY - 2015///0504 KW - Aged KW - Angiotensin II KW - toxicity KW - Animals KW - Coronary Disease KW - blood KW - Endothelial Cells KW - metabolism KW - Endothelium, Vascular KW - Female KW - Free Radical Scavengers KW - pharmacology KW - Gene Expression Regulation KW - Genes, Reporter KW - HEK293 Cells KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Hydrogen Peroxide KW - Hypercholesterolemia KW - genetics KW - Immunity, Innate KW - Inflammasomes KW - Interleukin-1beta KW - Kruppel-Like Factor 4 KW - Lipoproteins, LDL KW - Male KW - Mice KW - Mice, Transgenic KW - MicroRNAs KW - biosynthesis KW - Middle Aged KW - Organometallic Compounds KW - Oxidative Stress KW - Recombinant Fusion Proteins KW - Salicylates KW - Sterol Regulatory Element Binding Protein 2 KW - Transcriptional Activation KW - Zebrafish KW - Zebrafish Proteins KW - physiology N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1161/CIRCULATIONAHA.114.013675 ER -