Alvarez-Calderon, Francesca <br/><br/>
Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Mar 2015 
 - 1360-72 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1557-3265 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-14-2146  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Dihydrolipoyllysine-Residue Acetyltransferase--genetics<br/>Disease Models, Animal<br/>Female<br/>Fusion Proteins, bcr-abl--metabolism<br/>Humans<br/>Imatinib Mesylate--pharmacology<br/>Ketone Oxidoreductases--metabolism<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Inbred NOD<br/>Mice, Knockout<br/>Mitochondria--metabolism<br/>Mitochondrial Proteins--genetics<br/>Mitochondrial Proton-Translocating ATPases--antagonists & inhibitors<br/>Oligomycins--pharmacology<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>RNA Interference<br/>RNA, Small Interfering<br/>Superoxides--metabolism<br/>fms-Like Tyrosine Kinase 3--genetics