TY - GEN AU - Budyak,Ivan L AU - Doyle,Brandon L AU - Weiss,William F TI - Technical decision-making with higher order structure data: specific binding of a nonionic detergent perturbs higher order structure of a therapeutic monoclonal antibody SN - 1520-6017 PY - 2015///1203 KW - Antibodies, Monoclonal KW - chemistry KW - Biological Products KW - Chemistry, Pharmaceutical KW - Decision Support Techniques KW - Detergents KW - Drug Discovery KW - methods KW - Drug Stability KW - Octoxynol KW - Protein Conformation KW - Protein Stability KW - Structure-Activity Relationship KW - Technology, Pharmaceutical KW - Temperature N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/jps.24293 ER -