TY - GEN AU - Chowdhury,Abhishek AU - Paul,Paulomi AU - Bhattacharjee,Amitabha AU - Talukdar,Anupam Das AU - Choudhury,Manabendra Dutta TI - Virtual high throughput screening of carbapenem derivatives as new generation carbapenemase and penicillin binding protein inhibitors: a hunt to save drug of last resort SN - 1875-5402 PY - 2015///0923 KW - Anti-Bacterial Agents KW - chemistry KW - Bacterial Infections KW - drug therapy KW - Bacterial Proteins KW - antagonists & inhibitors KW - Carbapenems KW - Computer-Aided Design KW - Drug Design KW - Drug Evaluation, Preclinical KW - Enzyme Inhibitors KW - High-Throughput Screening Assays KW - Humans KW - Klebsiella pneumoniae KW - enzymology KW - Methicillin-Resistant Staphylococcus aureus KW - Molecular Docking Simulation KW - Molecular Dynamics Simulation KW - Penicillin-Binding Proteins KW - beta-Lactamases KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2174/1386207317666141226131709 ER -