TY - GEN AU - Funato,Kosuke AU - Major,Tamara AU - Lewis,Peter W AU - Allis,C David AU - Tabar,Viviane TI - Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation SN - 1095-9203 PY - 2015///0115 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Brain Stem Neoplasms KW - genetics KW - Cell Transformation, Neoplastic KW - Child KW - Drug Screening Assays, Antitumor KW - Embryonic Stem Cells KW - metabolism KW - Epigenesis, Genetic KW - Gene Expression Regulation, Neoplastic KW - Genome-Wide Association Study KW - Glioma KW - Histones KW - Humans KW - Mice KW - Models, Genetic KW - Neural Stem Cells KW - Proto-Oncogene Proteins KW - antagonists & inhibitors KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1253799 ER -