TY  - GEN
AU  - Knapman,Alisa
AU  - Santiago,Marina
AU  - Connor,Mark
TI  - A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro
SN  - 1476-5381
PY  - 2016///0105
KW  - Adenylyl Cyclase Inhibitors
KW  - pharmacology
KW  - Adenylyl Cyclases
KW  - metabolism
KW  - Analgesics, Opioid
KW  - Animals
KW  - Buprenorphine
KW  - CHO Cells
KW  - Cricetulus
KW  - Dose-Response Relationship, Drug
KW  - Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
KW  - Fentanyl
KW  - G Protein-Coupled Inwardly-Rectifying Potassium Channels
KW  - agonists
KW  - Genotype
KW  - Humans
KW  - Ion Channel Gating
KW  - drug effects
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinase 3
KW  - Morphine
KW  - Phenotype
KW  - Phosphorylation
KW  - Polymorphism, Single Nucleotide
KW  - Receptors, Opioid, mu
KW  - Signal Transduction
KW  - Time Factors
KW  - Transfection
KW  - beta-Endorphin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/bph.13047
ER  -