Smith, Joshua A

Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury. [electronic resource] - The Journal of pharmacology and experimental therapeutics Feb 2015 - 346-57 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1521-0103

10.1124/jpet.114.221085 doi


Acute Kidney Injury--chemically induced
Animals
DNA, Mitochondrial--metabolism
Disease Models, Animal
Dose-Response Relationship, Drug
Endotoxins--toxicity
Extracellular Signal-Regulated MAP Kinases--antagonists & inhibitors
Kidney Cortex--drug effects
Kidney Function Tests
MAP Kinase Signaling System--drug effects
Male
Mice, Inbred C57BL
Mice, Knockout
Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Toll-Like Receptor 4--genetics
Transcription Factors--antagonists & inhibitors