TY - GEN AU - Gordian,Edna AU - Li,Jiannong AU - Pevzner,Yuri AU - Mediavilla-Varela,Melanie AU - Luddy,Kimberly AU - Ohaegbulam,Kim AU - Daniel,Kenyon G AU - Haura,Eric B AU - Muñoz-Antonia,Teresita TI - Transforming growth factor β signaling overcomes dasatinib resistance in lung cancer SN - 1932-6203 PY - 2015///0928 KW - Aniline Compounds KW - metabolism KW - Antineoplastic Agents KW - Antineoplastic Combined Chemotherapy Protocols KW - Apoptosis KW - drug effects KW - Carcinoma, Non-Small-Cell Lung KW - pathology KW - Cell Line, Tumor KW - Dasatinib KW - Drug Resistance, Neoplasm KW - Humans KW - Intracellular Space KW - Lung Neoplasms KW - Molecular Docking Simulation KW - Nitriles KW - Protein Conformation KW - Protein Serine-Threonine Kinases KW - chemistry KW - Pyrimidines KW - Quinolines KW - Receptor, Transforming Growth Factor-beta Type I KW - Receptors, Transforming Growth Factor beta KW - Signal Transduction KW - Smad3 Protein KW - Thiazoles KW - Transforming Growth Factor beta N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1371/journal.pone.0114131 ER -