TY  - GEN
AU  - Duprex,W Paul
AU  - Fouchier,Ron A M
AU  - Imperiale,Michael J
AU  - Lipsitch,Marc
AU  - Relman,David A
TI  - Gain-of-function experiments: time for a real debate
SN  - 1740-1534
PY  - 2015///0209
KW  - Biomedical Research
KW  - ethics
KW  - Humans
KW  - Influenza, Human
KW  - Orthomyxoviridae
KW  - pathogenicity
KW  - Pandemics
KW  - prevention & control
KW  - Phenotype
KW  - Research Design
KW  - Risk Assessment
N1  - Publication Type: Review; Journal Article
UR  - https://doi.org/10.1038/nrmicro3405
ER  -