Pan, Yong <br/><br/>
PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway.  [electronic resource] 

 -  Investigational new drugs  Apr 2015 
 - 271-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1573-0646 
<br/><br/><label>Standard No.: </label>10.1007/s10637-014-0190-6  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cardiac Glycosides--pharmacology<br/>Cell Cycle<br/>Cell Line, Tumor<br/>Class Ib Phosphatidylinositol 3-Kinase--biosynthesis<br/>Deoxycytidine--analogs & derivatives<br/>Down-Regulation<br/>Female<br/>Humans<br/>Mice<br/>Mice, Inbred BALB C<br/>Nerium<br/>Pancreatic Neoplasms--drug therapy<br/>Plant Extracts--pharmacology<br/>Proto-Oncogene Proteins c-akt--biosynthesis<br/>TOR Serine-Threonine Kinases--biosynthesis<br/>Gemcitabine