Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. [electronic resource]
- Journal of neuropathology and experimental neurology Jan 2015
- 25-37 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1554-6578
10.1097/NEN.0000000000000146 doi
Blood-Brain Barrier--metabolism Brain Neoplasms--pathology Capillary Permeability--genetics Cells, Cultured Claudin-5--metabolism Electric Impedance Endothelial Cells--metabolism Gene Expression Regulation, Neoplastic--genetics Glioma--pathology Green Fluorescent Proteins--genetics Humans Intercellular Signaling Peptides and Proteins--metabolism Matrix Metalloproteinase 9--metabolism Nerve Tissue Proteins--metabolism Occludin--metabolism Receptors, Cell Surface--genetics Signal Transduction--genetics Tight Junction Proteins--genetics Transendothelial and Transepithelial Migration--physiology Zonula Occludens-1 Protein--metabolism src-Family Kinases--metabolism Slit Homolog 2 Protein