Nagesh, Narayana <br/><br/>
A dihydroindolizino indole derivative selectively stabilizes G-quadruplex DNA and down-regulates c-MYC expression in human cancer cells.  [electronic resource] 

 -  Biochimica et biophysica acta  Jan 2015 
 - 129-40 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-3002 
<br/><br/><label>Standard No.: </label>10.1016/j.bbagen.2014.10.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Binding, Competitive<br/>Calorimetry<br/>Cell Line, Tumor<br/>Cell Movement--drug effects<br/>Cell Proliferation--drug effects<br/>DNA--chemistry<br/>Down-Regulation--drug effects<br/>G-Quadruplexes<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>HeLa Cells<br/>Humans<br/>Indoles--chemical synthesis<br/>MCF-7 Cells<br/>Models, Chemical<br/>Molecular Structure<br/>Neoplasms--genetics<br/>Proto-Oncogene Proteins c-myc--genetics<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Spectrometry, Mass, Electrospray Ionization<br/>Spectrophotometry<br/>Transition Temperature--drug effects