TY - GEN AU - Suttle,A Benjamin AU - Grossmann,Kenneth F AU - Ouellet,Daniele AU - Richards-Peterson,Lauren E AU - Aktan,Gursel AU - Gordon,Michael S AU - LoRusso,Patricia M AU - Infante,Jeffrey R AU - Sharma,Sunil AU - Kendra,Kari AU - Patel,Manish AU - Pant,Shubham AU - Arkenau,Hendrik-Tobias AU - Middleton,Mark R AU - Blackman,Samuel C AU - Botbyl,Jeff AU - Carson,Stanley W TI - Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib SN - 1552-4604 PY - 2016///0314 KW - Anticoagulants KW - pharmacokinetics KW - Cytochrome P-450 CYP2C8 Inhibitors KW - pharmacology KW - Cytochrome P-450 CYP3A Inhibitors KW - Drug Interactions KW - Female KW - Gemfibrozil KW - Humans KW - Imidazoles KW - administration & dosage KW - Ketoconazole KW - Male KW - Middle Aged KW - Oximes KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins B-raf KW - antagonists & inhibitors KW - Warfarin N1 - Publication Type: Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jcph.437 ER -