TY - GEN AU - Wang,Xiao-Kun AU - To,Kenneth Kin Wah AU - Huang,Li-Yan AU - Xu,Jing-Hong AU - Yang,Ke AU - Wang,Fang AU - Huang,Zhen-Cong AU - Ye,Sheng AU - Fu,Li-Wu TI - Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo SN - 1949-2553 PY - 2015///1020 KW - ATP Binding Cassette Transporter, Subfamily G, Member 2 KW - ATP-Binding Cassette Transporters KW - antagonists & inhibitors KW - Afatinib KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Blotting, Western KW - Cell Line, Tumor KW - Drug Resistance, Multiple KW - drug effects KW - Drug Resistance, Neoplasm KW - Female KW - Flow Cytometry KW - Humans KW - Immunohistochemistry KW - In Vitro Techniques KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Neoplasm Proteins KW - Neoplasms, Experimental KW - drug therapy KW - Quinazolines KW - Real-Time Polymerase Chain Reaction KW - Topotecan KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.18632/oncotarget.2647 ER -