Danzhi Xiaoyao San ameliorates depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase. [electronic resource]
- Journal of ethnopharmacology Feb 2015
- 86-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7573
10.1016/j.jep.2014.11.031 doi
Animals Antidepressive Agents--pharmacology Behavior, Animal--drug effects Cytokines--blood Down-Regulation--drug effects Drugs, Chinese Herbal--pharmacology Fluoxetine--pharmacology Hippocampus--drug effects Indoleamine-Pyrrole 2,3,-Dioxygenase--metabolism Kynurenine--biosynthesis Male Motor Activity--drug effects Rats Serotonin--metabolism Tryptophan--metabolism Up-Regulation--drug effects