TY - GEN AU - Dugan,Jae AU - Griffiths,Eric AU - Snow,Paige AU - Rosenzweig,Holly AU - Lee,Ellen AU - Brown,Brieanna AU - Carr,Daniel W AU - Rose,Carlos AU - Rosenbaum,James AU - Davey,Michael P TI - Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice SN - 1550-6606 PY - 2016///0226 KW - Acetylmuramyl-Alanyl-Isoglutamine KW - immunology KW - Animals KW - Arthritis KW - genetics KW - Cell Line KW - Gene Knock-In Techniques KW - HEK293 Cells KW - Humans KW - Interleukin-6 KW - biosynthesis KW - Macrophages KW - drug effects KW - Mice KW - Mice, Inbred C57BL KW - Mitogen-Activated Protein Kinases KW - metabolism KW - Mutation KW - NF-kappa B KW - Nod2 Signaling Adaptor Protein KW - Phosphorylation KW - Protein Processing, Post-Translational KW - RNA Interference KW - RNA, Small Interfering KW - Receptor-Interacting Protein Serine-Threonine Kinase 2 KW - Sarcoidosis KW - Signal Transduction KW - Synovitis KW - Ubiquitination KW - Uveitis KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.1402330 ER -