TY  - GEN
AU  - Wiegering,Armin
AU  - Korb,Doreen
AU  - Thalheimer,Andreas
AU  - Kämmerer,Ulrike
AU  - Allmanritter,Jan
AU  - Matthes,Niels
AU  - Linnebacher,Michael
AU  - Schlegel,Nicolas
AU  - Klein,Ingo
AU  - Ergün,Süleyman
AU  - Germer,Christoph-Thomas
AU  - Otto,Christoph
TI  - E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts
SN  - 1476-5586
PY  - 2015///0720
KW  - Animals
KW  - Caco-2 Cells
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - drug effects
KW  - Cells, Cultured
KW  - Colorectal Neoplasms
KW  - genetics
KW  - Female
KW  - Gene Expression
KW  - HCT116 Cells
KW  - HT29 Cells
KW  - Human Umbilical Vein Endothelial Cells
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Ki-67 Antigen
KW  - metabolism
KW  - Mice, Inbred Strains
KW  - Mice, Nude
KW  - Mutation
KW  - Neovascularization, Pathologic
KW  - prevention & control
KW  - Phenylurea Compounds
KW  - pharmacology
KW  - Protein Kinase Inhibitors
KW  - Quinolines
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Treatment Outcome
KW  - Xenograft Model Antitumor Assays
KW  - methods
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.neo.2014.09.008
ER  -