TY - GEN AU - Celik,Hamza AU - Mallaney,Cates AU - Kothari,Alok AU - Ostrander,Elizabeth L AU - Eultgen,Elizabeth AU - Martens,Andrew AU - Miller,Christopher A AU - Hundal,Jasreet AU - Klco,Jeffery M AU - Challen,Grant A TI - Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation SN - 1528-0020 PY - 2015///0324 KW - Animals KW - Blast Crisis KW - genetics KW - Bone Marrow KW - enzymology KW - Cell Differentiation KW - Cell Line KW - Cell Transformation, Neoplastic KW - DNA (Cytosine-5-)-Methyltransferases KW - DNA Methyltransferase 3A KW - Hematopoiesis KW - Hematopoietic Stem Cells KW - Leukemia, Myeloid, Acute KW - Mice KW - Mice, Knockout KW - Mutation KW - Proto-Oncogene Proteins c-kit N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2014-08-594564 ER -