TY - GEN AU - Kim,Jihun AU - Fox,Cameron AU - Peng,Shouyong AU - Pusung,Mark AU - Pectasides,Eirini AU - Matthee,Eric AU - Hong,Yong Sang AU - Do,In-Gu AU - Jang,Jiryeon AU - Thorner,Aaron R AU - Van Hummelen,Paul AU - Rustgi,Anil K AU - Wong,Kwok-Kin AU - Zhou,Zhongren AU - Tang,Ping AU - Kim,Kyoung-Mee AU - Lee,Jeeyun AU - Bass,Adam J TI - Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma SN - 1558-8238 PY - 2015///0708 KW - Adenocarcinoma KW - drug therapy KW - Antibodies, Monoclonal, Humanized KW - administration & dosage KW - Antineoplastic Agents KW - Biomarkers, Tumor KW - genetics KW - Drug Resistance, Neoplasm KW - ErbB Receptors KW - Esophageal Neoplasms KW - diet therapy KW - Female KW - Gene Amplification KW - drug effects KW - Humans KW - Male KW - Phosphatidylinositol 3-Kinases KW - Receptor, ErbB-2 KW - Stomach Neoplasms KW - Trastuzumab N1 - Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI75200 ER -