TY - GEN AU - Laurent,Pierre-Alexandre AU - Séverin,Sonia AU - Hechler,Béatrice AU - Vanhaesebroeck,Bart AU - Payrastre,Bernard AU - Gratacap,Marie-Pierre TI - Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate SN - 1528-0020 PY - 2015///0413 KW - Animals KW - Blood Platelets KW - drug effects KW - Class I Phosphatidylinositol 3-Kinases KW - antagonists & inhibitors KW - Gene Expression Regulation KW - Glycogen Synthase Kinase 3 KW - Humans KW - Mechanotransduction, Cellular KW - Mice KW - Mice, Transgenic KW - Phosphorylation KW - Platelet Aggregation KW - Proto-Oncogene Proteins c-akt KW - genetics KW - Pyridines KW - pharmacology KW - Pyrimidines KW - Pyrimidinones KW - Stress, Mechanical KW - Thrombosis KW - enzymology KW - ortho-Aminobenzoates N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2014-07-588335 ER -