Portoghese, P S <br/><br/>
Synthesis and pharmacologic characterization of an alkylating analogue (chlornaltrexamine) of naltrexone with ultralong-lasting narcotic antagonist properties.  [electronic resource] 

 -  Journal of medicinal chemistry  Feb 1979 
 - 168-73 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm00188a008  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkylating Agents--chemical synthesis<br/>Analgesics<br/>Animals<br/>Humans<br/>In Vitro Techniques<br/>Male<br/>Mice<br/>Molecular Conformation<br/>Morphine--antagonists & inhibitors<br/>Morphine Dependence--prevention & control<br/>Naloxone--analogs & derivatives<br/>Naltrexone--analogs & derivatives<br/>Narcotic Antagonists--chemical synthesis<br/>Nitrogen Mustard Compounds--chemical synthesis<br/>Rats<br/>Receptors, Opioid--metabolism<br/>Time Factors