TY - GEN AU - Smith,Sheena N AU - Wang,Yuhang AU - Baylon,Javier L AU - Singh,Nishant K AU - Baker,Brian M AU - Tajkhorshid,Emad AU - Kranz,David M TI - Changing the peptide specificity of a human T-cell receptor by directed evolution SN - 2041-1723 PY - 2016///0222 KW - Amino Acid Sequence KW - Clone Cells KW - Complementarity Determining Regions KW - chemistry KW - Epitopes KW - Evolution, Molecular KW - HLA-A2 Antigen KW - Humans KW - In Vitro Techniques KW - MART-1 Antigen KW - Major Histocompatibility Complex KW - Models, Molecular KW - Molecular Sequence Data KW - Mutation KW - Oligopeptides KW - Protein Binding KW - Protein Conformation KW - Receptors, Antigen, T-Cell N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncomms6223 ER -