TY  - GEN
AU  - Huelsemann,M F
AU  - Patz,M
AU  - Beckmann,L
AU  - Brinkmann,K
AU  - Otto,T
AU  - Fandrey,J
AU  - Becker,H J
AU  - Theurich,S
AU  - von Bergwelt-Baildon,M
AU  - Pallasch,C P
AU  - Zahedi,R P
AU  - Kashkar,H
AU  - Reinhardt,H C
AU  - Hallek,M
AU  - Wendtner,C M
AU  - Frenzel,L P
TI  - Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia
SN  - 1476-5551
PY  - 2015///0604
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - B-Lymphocytes
KW  - drug effects
KW  - Bendamustine Hydrochloride
KW  - Biphenyl Compounds
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - CD40 Ligand
KW  - genetics
KW  - Cell Hypoxia
KW  - Cells, Cultured
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Activation
KW  - Gene Expression Regulation, Leukemic
KW  - Humans
KW  - Leukemia, Lymphocytic, Chronic, B-Cell
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - antagonists & inhibitors
KW  - Nitrogen Mustard Compounds
KW  - Nitrophenols
KW  - Oxygen
KW  - Piperazines
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Signal Transduction
KW  - Sulfonamides
KW  - Vidarabine
KW  - analogs & derivatives
KW  - bcl-X Protein
KW  - p38 Mitogen-Activated Protein Kinases
N1  - Publication Type: Letter; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/leu.2014.320
ER  -