Xu, Gong-Ping

Matrine inhibits the growth and induces apoptosis of osteosarcoma cells in vitro by inactivating the Akt pathway. [electronic resource] - Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Mar 2015 - 1653-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1423-0380

10.1007/s13277-014-2764-5 doi


Alkaloids--pharmacology
Apoptosis--drug effects
Bone Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin D1--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
G1 Phase Cell Cycle Checkpoints--drug effects
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Osteosarcoma--drug therapy
Proto-Oncogene Proteins c-akt--metabolism
Quinolizines--pharmacology
Resting Phase, Cell Cycle--drug effects
Signal Transduction--drug effects
bcl-2-Associated X Protein--metabolism
Matrines