TY  - GEN
AU  - Wood,D C
AU  - Pelc,L A
AU  - Pozzi,N
AU  - Wallisch,M
AU  - Verbout,N G
AU  - Tucker,E I
AU  - Gruber,A
AU  - Di Cera,E
TI  - WEDGE: an anticoagulant thrombin mutant produced by autoactivation
SN  - 1538-7836
PY  - 2016///0303
KW  - Amino Acid Substitution
KW  - Animals
KW  - Anticoagulants
KW  - administration & dosage
KW  - Blood Coagulation
KW  - drug effects
KW  - Catalysis
KW  - Enzyme Activation
KW  - Injections, Intravenous
KW  - Mutation
KW  - Papio
KW  - Partial Thromboplastin Time
KW  - Protein Engineering
KW  - methods
KW  - Prothrombin
KW  - Recombinant Proteins
KW  - biosynthesis
KW  - Thrombin
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1111/jth.12774
ER  -