TY - GEN AU - Gu,Mingxia AU - Mordwinkin,Nicholas M AU - Kooreman,Nigel G AU - Lee,Jaecheol AU - Wu,Haodi AU - Hu,Shijun AU - Churko,Jared M AU - Diecke,Sebastian AU - Burridge,Paul W AU - He,Chunjiang AU - Barron,Frances E AU - Ong,Sang-Ging AU - Gold,Joseph D AU - Wu,Joseph C TI - Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism SN - 1522-9645 PY - 2015///1228 KW - Analysis of Variance KW - Animals KW - Apoptosis KW - physiology KW - Cell Differentiation KW - Diet, High-Fat KW - Endothelial Cells KW - Enzyme Inhibitors KW - pharmacology KW - Fibroblasts KW - Hindlimb KW - blood supply KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Induced Pluripotent Stem Cells KW - Injections, Intramuscular KW - Ischemia KW - physiopathology KW - Mice, Inbred C57BL KW - Muscle, Skeletal KW - Muscular Diseases KW - prevention & control KW - NG-Nitroarginine Methyl Ester KW - Nitric Oxide KW - Nitric Oxide Synthase Type III KW - metabolism KW - Obesity KW - Oxidative Stress KW - Pravastatin KW - Proto-Oncogene Proteins c-akt KW - Random Allocation KW - Reperfusion Injury KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/eurheartj/ehu411 ER -