TY - GEN AU - Huang,Yu-Hwa AU - Zhu,Chen AU - Kondo,Yasuyuki AU - Anderson,Ana C AU - Gandhi,Amit AU - Russell,Andrew AU - Dougan,Stephanie K AU - Petersen,Britt-Sabina AU - Melum,Espen AU - Pertel,Thomas AU - Clayton,Kiera L AU - Raab,Monika AU - Chen,Qiang AU - Beauchemin,Nicole AU - Yazaki,Paul J AU - Pyzik,Michal AU - Ostrowski,Mario A AU - Glickman,Jonathan N AU - Rudd,Christopher E AU - Ploegh,Hidde L AU - Franke,Andre AU - Petsko,Gregory A AU - Kuchroo,Vijay K AU - Blumberg,Richard S TI - CEACAM1 regulates TIM-3-mediated tolerance and exhaustion SN - 1476-4687 PY - 2015///0202 KW - Animals KW - Antigens, CD KW - chemistry KW - Autoimmunity KW - immunology KW - Cell Adhesion Molecules KW - Cell Line KW - Colorectal Neoplasms KW - Disease Models, Animal KW - Female KW - Hepatitis A Virus Cellular Receptor 2 KW - Humans KW - Immune Tolerance KW - Inflammation KW - Ligands KW - Male KW - Membrane Proteins KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Models, Molecular KW - Mucous Membrane KW - Protein Conformation KW - Protein Multimerization KW - Receptors, Virus KW - T-Lymphocytes N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/nature13848 ER -