Umapathy, Ganesh

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma. [electronic resource] - Science signaling Oct 2014 - ra102 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1937-9145

10.1126/scisignal.2005470 doi


Anaplastic Lymphoma Kinase
Animals
Cell Line, Tumor
DNA Primers--genetics
Fluorescent Antibody Technique
Gene Expression Regulation, Neoplastic--genetics
Green Fluorescent Proteins
Humans
Image Processing, Computer-Assisted
Immunoblotting
Immunohistochemistry
Immunoprecipitation
Magnetic Resonance Imaging
Mitogen-Activated Protein Kinase 7--genetics
N-Myc Proto-Oncogene Protein
Neuroblastoma--metabolism
Nuclear Proteins--metabolism
Oncogene Proteins--metabolism
PC12 Cells
RNA Interference
Rats
Real-Time Polymerase Chain Reaction
Receptor Protein-Tyrosine Kinases--metabolism