Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress. [electronic resource]
- Nature cell biology Dec 2014
- 1227-37 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-4679
10.1038/ncb3054 doi
Animals Cell Line, Tumor Crystallography, X-Ray Endosomal Sorting Complexes Required for Transport--genetics HSP40 Heat-Shock Proteins--metabolism HeLa Cells Heat-Shock Response--physiology Hot Temperature Humans Mice Nedd4 Ubiquitin Protein Ligases Peptide Termination Factors--metabolism Protein Folding Protein Structure, Tertiary Pyruvate Decarboxylase--metabolism Pyruvate Kinase--genetics Saccharomyces cerevisiae--enzymology Saccharomyces cerevisiae Proteins--genetics Ubiquitin--metabolism Ubiquitin-Protein Ligase Complexes--genetics Ubiquitin-Protein Ligases--genetics Ubiquitination