TY - GEN AU - Ilie,M I AU - Bence,C AU - Hofman,V AU - Long-Mira,E AU - Butori,C AU - Bouhlel,L AU - Lalvée,S AU - Mouroux,J AU - Poudenx,M AU - Otto,J AU - Marquette,C H AU - Hofman,P TI - Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK 'borderline'-positive rearrangements or a high copy number: a potential major issue for anti-ALK therapeutic strategies SN - 1569-8041 PY - 2015///0824 KW - Adenocarcinoma KW - drug therapy KW - Adenocarcinoma of Lung KW - Adult KW - Aged KW - Aged, 80 and over KW - Anaplastic Lymphoma Kinase KW - Crizotinib KW - Female KW - Fluorescent Antibody Technique KW - methods KW - Gene Dosage KW - genetics KW - Gene Rearrangement KW - Genetic Variation KW - Humans KW - In Situ Hybridization, Fluorescence KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Protein Kinase Inhibitors KW - therapeutic use KW - Protein-Tyrosine Kinases KW - analysis KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-met KW - Pyrazoles KW - Pyridines KW - Receptor Protein-Tyrosine Kinases N1 - Publication Type: Journal Article UR - https://doi.org/10.1093/annonc/mdu484 ER -