TY  - GEN
AU  - Lord,Christopher J
AU  - Tutt,Andrew N J
AU  - Ashworth,Alan
TI  - Synthetic lethality and cancer therapy: lessons learned from the development of PARP inhibitors
SN  - 1545-326X
PY  - 2015///0914
KW  - Benzamides
KW  - therapeutic use
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Inhibitors
KW  - Female
KW  - Genes, BRCA1
KW  - Genes, BRCA2
KW  - Humans
KW  - Mutation
KW  - Neoplasms
KW  - Neoplasms, Cystic, Mucinous, and Serous
KW  - Ovarian Neoplasms
KW  - Phthalazines
KW  - Piperazines
KW  - Poly (ADP-Ribose) Polymerase-1
KW  - Poly(ADP-ribose) Polymerase Inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
UR  - https://doi.org/10.1146/annurev-med-050913-022545
ER  -