TY - GEN AU - DaRosa,Paul A AU - Wang,Zhizhi AU - Jiang,Xiaomo AU - Pruneda,Jonathan N AU - Cong,Feng AU - Klevit,Rachel E AU - Xu,Wenqing TI - Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal SN - 1476-4687 PY - 2015///0219 KW - Adenosine Diphosphate Ribose KW - chemistry KW - Allosteric Regulation KW - Animals KW - Biocatalysis KW - Crystallography, X-Ray KW - Enzyme Activation KW - Humans KW - Ligands KW - Mice KW - Models, Molecular KW - Poly Adenosine Diphosphate Ribose KW - Protein Binding KW - Protein Processing, Post-Translational KW - Protein Structure, Tertiary KW - Substrate Specificity KW - Tankyrases KW - metabolism KW - Ubiquitin-Conjugating Enzymes KW - Ubiquitin-Protein Ligases KW - Ubiquitination N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1038/nature13826 ER -