TY - GEN AU - Zhang,Yaping AU - Hsu,Cheng-Pang AU - Lu,Jian-Feng AU - Kuchimanchi,Mita AU - Sun,Yu-Nien AU - Ma,Ji AU - Xu,Guifen AU - Zhang,Yilong AU - Xu,Yang AU - Weidner,Margaret AU - Huard,Justin AU - D'Argenio,David Z TI - FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia SN - 1573-8744 PY - 2015///0707 KW - Animals KW - Benzothiazoles KW - pharmacology KW - Cell Line, Tumor KW - Cyclin-Dependent Kinase 4 KW - antagonists & inhibitors KW - Cyclin-Dependent Kinase 6 KW - Disease Models, Animal KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Mice KW - Niacinamide KW - analogs & derivatives KW - Phenylurea Compounds KW - Protein Kinase Inhibitors KW - Signal Transduction KW - drug effects KW - Sorafenib KW - Tumor Burden KW - fms-Like Tyrosine Kinase 3 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s10928-014-9393-x ER -