TY  - GEN
AU  - Ronan,Baptiste
AU  - Flamand,Odile
AU  - Vescovi,Lionel
AU  - Dureuil,Christine
AU  - Durand,Laurence
AU  - Fassy,Florence
AU  - Bachelot,Marie-France
AU  - Lamberton,Annabelle
AU  - Mathieu,Magali
AU  - Bertrand,Thomas
AU  - Marquette,Jean-Pierre
AU  - El-Ahmad,Youssef
AU  - Filoche-Romme,Bruno
AU  - Schio,Laurent
AU  - Garcia-Echeverria,Carlos
AU  - Goulaouic,Hélène
AU  - Pasquier,Benoit
TI  - A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy
SN  - 1552-4469
PY  - 2015///0122
KW  - Adenosine Triphosphate
KW  - chemistry
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Autophagy
KW  - drug effects
KW  - Catalytic Domain
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Class III Phosphatidylinositol 3-Kinases
KW  - antagonists & inhibitors
KW  - Drug Synergism
KW  - Endosomes
KW  - Everolimus
KW  - Gene Expression
KW  - Humans
KW  - Kidney
KW  - enzymology
KW  - Kinetics
KW  - Lysosomes
KW  - Molecular Docking Simulation
KW  - Protein Kinase Inhibitors
KW  - Pyridines
KW  - Pyrimidinones
KW  - Recombinant Proteins
KW  - Signal Transduction
KW  - Sirolimus
KW  - analogs & derivatives
KW  - TOR Serine-Threonine Kinases
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/nchembio.1681
ER  -