TY - GEN AU - Liu,Yubo AU - Xie,Mingzhou AU - Song,Ting AU - Sheng,Hongkun AU - Yu,Xiaoyan AU - Zhang,Zhichao TI - A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1 SN - 1755-148X PY - 2015///1116 KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Bcl-2-Like Protein 11 KW - Caspases KW - Cell Line, Tumor KW - Extracellular Signal-Regulated MAP Kinases KW - Gossypol KW - pharmacology KW - Humans KW - JNK Mitogen-Activated Protein Kinases KW - Melanoma KW - pathology KW - Membrane Proteins KW - Mice KW - Mitochondria KW - Myeloid Cell Leukemia Sequence 1 Protein KW - Phosphorylation KW - Proteolysis KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Signal Transduction KW - Substrate Specificity KW - bcl-2 Homologous Antagonist-Killer Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/pcmr.12325 ER -