Zou, Taisong <br/><br/>
Evolution of conformational dynamics determines the conversion of a promiscuous generalist into a specialist enzyme.  [electronic resource] 

 -  Molecular biology and evolution  Jan 2015 
 - 132-43 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1537-1719 
<br/><br/><label>Standard No.: </label>10.1093/molbev/msu281  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Anti-Bacterial Agents--metabolism<br/>Bacteria--enzymology<br/>Catalytic Domain<br/>Evolution, Molecular<br/>Molecular Dynamics Simulation<br/>Mutation<br/>Principal Component Analysis<br/>Protein Structure, Tertiary<br/>Substrate Specificity<br/>beta-Lactamases--chemistry