TY  - GEN
AU  - Peirs,Sofie
AU  - Matthijssens,Filip
AU  - Goossens,Steven
AU  - Van de Walle,Inge
AU  - Ruggero,Katia
AU  - de Bock,Charles E
AU  - Degryse,Sandrine
AU  - Canté-Barrett,Kirsten
AU  - Briot,Delphine
AU  - Clappier,Emmanuelle
AU  - Lammens,Tim
AU  - De Moerloose,Barbara
AU  - Benoit,Yves
AU  - Poppe,Bruce
AU  - Meijerink,Jules P
AU  - Cools,Jan
AU  - Soulier,Jean
AU  - Rabbitts,Terence H
AU  - Taghon,Tom
AU  - Speleman,Frank
AU  - Van Vlierberghe,Pieter
TI  - ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
SN  - 1528-0020
PY  - 2015///0220
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Blotting, Western
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - drug effects
KW  - Cells, Cultured
KW  - Child
KW  - Drug Synergism
KW  - Gene Expression Profiling
KW  - Gene Expression Regulation, Leukemic
KW  - HEK293 Cells
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Jurkat Cells
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Oligonucleotide Array Sequence Analysis
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - drug therapy
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - antagonists & inhibitors
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sulfonamides
KW  - Survival Analysis
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1182/blood-2014-05-574566
ER  -