TY - GEN AU - Wegiel,Barbara AU - Larsen,Rasmus AU - Gallo,David AU - Chin,Beek Yoke AU - Harris,Clair AU - Mannam,Praveen AU - Kaczmarek,Elzbieta AU - Lee,Patty J AU - Zuckerbraun,Brian S AU - Flavell,Richard AU - Soares,Miguel P AU - Otterbein,Leo E TI - Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation SN - 1558-8238 PY - 2015///0302 KW - Adenosine Triphosphate KW - biosynthesis KW - Administration, Inhalation KW - Animals KW - Carbon Monoxide KW - administration & dosage KW - Carrier Proteins KW - metabolism KW - Cells, Cultured KW - Escherichia coli KW - immunology KW - Heme Oxygenase-1 KW - Host-Pathogen Interactions KW - Inflammasomes KW - physiology KW - Interleukin-1beta KW - Macrophages KW - enzymology KW - Male KW - Membrane Proteins KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Phagocytosis KW - Potassium KW - Sepsis KW - drug therapy N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI72853 ER -