TY - GEN AU - Persaud,Avinash AU - Alberts,Philipp AU - Mari,Sara AU - Tong,Jiefei AU - Murchie,Ryan AU - Maspero,Elena AU - Safi,Frozan AU - Moran,Michael F AU - Polo,Simona AU - Rotin,Daniela TI - Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity SN - 1937-9145 PY - 2015///0615 KW - DNA, Complementary KW - genetics KW - Endocytosis KW - physiology KW - Endosomal Sorting Complexes Required for Transport KW - metabolism KW - Enzyme-Linked Immunosorbent Assay KW - Epidermal Growth Factor KW - Gene Knockdown Techniques KW - HeLa Cells KW - Humans KW - Immunoprecipitation KW - Models, Molecular KW - Mutagenesis, Site-Directed KW - Nedd4 Ubiquitin Protein Ligases KW - Phosphorylation KW - Proteolysis KW - Real-Time Polymerase Chain Reaction KW - Receptor Cross-Talk KW - Receptor, Fibroblast Growth Factor, Type 1 KW - Tandem Mass Spectrometry KW - Tyrosine KW - Ubiquitin-Protein Ligases KW - Ubiquitination N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/scisignal.2005290 ER -