TY - GEN AU - Bola,Becky M AU - Chadwick,Amy L AU - Michopoulos,Filippos AU - Blount,Kathryn G AU - Telfer,Brian A AU - Williams,Kaye J AU - Smith,Paul D AU - Critchlow,Susan E AU - Stratford,Ian J TI - Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport SN - 1538-8514 PY - 2015///0811 KW - Animals KW - Biological Transport KW - Cell Line, Tumor KW - Cluster Analysis KW - Disease Models, Animal KW - Female KW - Glycolysis KW - drug effects KW - Humans KW - Lactates KW - metabolism KW - Metabolomics KW - Monocarboxylic Acid Transporters KW - antagonists & inhibitors KW - Neoplasms KW - drug therapy KW - Oxidative Stress KW - Pyrimidinones KW - administration & dosage KW - Radiation Tolerance KW - Symporters KW - Thiophenes KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1535-7163.MCT-13-1091 ER -