TY - GEN AU - Buckley,Maria M AU - O'Halloran,Ken D AU - Rae,Mark G AU - Dinan,Timothy G AU - O'Malley,Dervla TI - Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome SN - 1469-7793 PY - 2015///0724 KW - Adolescent KW - Adult KW - Aged KW - Animals KW - Antibodies, Monoclonal KW - administration & dosage KW - Case-Control Studies KW - Disease Models, Animal KW - Enteric Nervous System KW - physiopathology KW - Female KW - Gastrointestinal Motility KW - physiology KW - Humans KW - Interleukin-6 KW - Irritable Bowel Syndrome KW - etiology KW - Male KW - Middle Aged KW - Myenteric Plexus KW - Neuroimmunomodulation KW - Neurosecretory Systems KW - Pain Threshold KW - drug effects KW - Pyrimidines KW - Pyrroles KW - Rats KW - Rats, Inbred WKY KW - Rats, Sprague-Dawley KW - Receptors, Corticotropin-Releasing Hormone KW - antagonists & inhibitors KW - Receptors, Interleukin-6 KW - Visceral Pain KW - Young Adult KW - CRF Receptor, Type 1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1113/jphysiol.2014.279968 ER -