TY - GEN AU - Tripathi,Kaushlendra AU - Mani,Chinnadurai AU - Barnett,Reagan AU - Nalluri,Sriram AU - Bachaboina,Lavanya AU - Rocconi,Rodney P AU - Athar,Mohammed AU - Owen,Laurie B AU - Palle,Komaraiah TI - Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors SN - 1083-351X PY - 2015///0117 KW - Antineoplastic Agents KW - chemistry KW - BH3 Interacting Domain Death Agonist Protein KW - metabolism KW - Binding Sites KW - Camptothecin KW - Cell Cycle KW - Cell Line, Tumor KW - Cell Survival KW - Checkpoint Kinase 1 KW - DNA Repair KW - Down-Regulation KW - Drug Resistance KW - Fibroblasts KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Phosphorylation KW - Promoter Regions, Genetic KW - Protein Kinases KW - RNA Interference KW - RNA, Small Interfering KW - Replication Protein A KW - S Phase KW - Signal Transduction KW - Topoisomerase I Inhibitors KW - Transcription Factors KW - Zinc Finger Protein GLI1 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M114.606483 ER -