Fennell, Dean A

Association between gene expression profiles and clinical outcome of pemetrexed-based treatment in patients with advanced non-squamous non-small cell lung cancer: exploratory results from a phase II study. [electronic resource] - PloS one 2014 - e107455 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0107455 doi


Adenocarcinoma--drug therapy
Aged
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Carcinoma, Non-Small-Cell Lung--drug therapy
Cisplatin--administration & dosage
Cluster Analysis
Disease-Free Survival
Female
Gene Expression Regulation, Neoplastic--drug effects
Glutamates--administration & dosage
Guanine--administration & dosage
Humans
Immunohistochemistry
Kaplan-Meier Estimate
Lung Neoplasms--drug therapy
Male
Middle Aged
Oligonucleotide Array Sequence Analysis
Outcome Assessment, Health Care--methods
Pemetrexed
Prognosis
Proportional Hazards Models
Thymidylate Synthase--genetics
Transcriptome--drug effects