TY - GEN AU - Kuiper,Justine L AU - Heideman,Danielle A M AU - Würdinger,Tom AU - Grünberg,Katrien AU - Groen,Harry J M AU - Smit,Egbert F TI - Rationale and study design of the IRENE-trial (NVALT-16): a phase II trial to evaluate iressa rechallenge in advanced NSCLC patients with an activating EGFR mutation who responded to an EGFR-TKI used as first-line or previous treatment SN - 1938-0690 PY - 2015///0730 KW - Antineoplastic Protocols KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Clinical Trials as Topic KW - Drug Resistance, Neoplasm KW - ErbB Receptors KW - genetics KW - Gefitinib KW - Humans KW - Lung Neoplasms KW - Mutation KW - Prospective Studies KW - Protein Kinase Inhibitors KW - administration & dosage KW - Quinazolines KW - Research Design KW - Survival Analysis KW - Withholding Treatment N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study UR - https://doi.org/10.1016/j.cllc.2014.07.008 ER -