TY  - GEN
AU  - Yi,Sha
AU  - Wen,Lu
AU  - He,Jing
AU  - Wang,Youping
AU  - Zhao,Fei
AU  - Zhao,Jie
AU  - Zhao,Zichu
AU  - Cui,Guohui
AU  - Chen,Yan
TI  - Deguelin, a selective silencer of the NPM1 mutant, potentiates apoptosis and induces differentiation in AML cells carrying the NPM1 mutation
SN  - 1432-0584
PY  - 2015///0420
KW  - Acute Disease
KW  - Apoptosis
KW  - drug effects
KW  - Blotting, Western
KW  - CCAAT-Enhancer-Binding Protein-alpha
KW  - metabolism
KW  - Caspase 6
KW  - Caspase 8
KW  - Cell Differentiation
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Dose-Response Relationship, Drug
KW  - Flow Cytometry
KW  - Humans
KW  - Leukemia, Myeloid
KW  - genetics
KW  - Mutant Proteins
KW  - Mutation
KW  - Nuclear Proteins
KW  - Nucleophosmin
KW  - RNA Interference
KW  - Rotenone
KW  - analogs & derivatives
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00277-014-2206-x
ER  -