BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. [electronic resource]
- Radiation oncology (London, England) Sep 2014
- 207 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1748-717X
10.1186/1748-717X-9-207 doi
Animals Antineoplastic Agents--pharmacology Blotting, Western Carcinoma, Squamous Cell--pathology Cell Hypoxia--drug effects Chemoradiotherapy--methods Dose Fractionation, Radiation Head and Neck Neoplasms--pathology Humans Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors Mice Mice, Nude Oxadiazoles--pharmacology Pyrazoles--pharmacology Radiation-Sensitizing Agents--pharmacology Squamous Cell Carcinoma of Head and Neck Xenograft Model Antitumor Assays