Helbig, Linda

BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. [electronic resource] - Radiation oncology (London, England) Sep 2014 - 207 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1748-717X

10.1186/1748-717X-9-207 doi


Animals
Antineoplastic Agents--pharmacology
Blotting, Western
Carcinoma, Squamous Cell--pathology
Cell Hypoxia--drug effects
Chemoradiotherapy--methods
Dose Fractionation, Radiation
Head and Neck Neoplasms--pathology
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors
Mice
Mice, Nude
Oxadiazoles--pharmacology
Pyrazoles--pharmacology
Radiation-Sensitizing Agents--pharmacology
Squamous Cell Carcinoma of Head and Neck
Xenograft Model Antitumor Assays