Liu, Ling <br/><br/>
LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Dec 2014 
 - 6059-70 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1557-3265 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-14-0543  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--administration & dosage<br/>Antibodies, Monoclonal, Humanized--pharmacology<br/>Antibodies, Neutralizing--administration & dosage<br/>Antineoplastic Agents--administration & dosage<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Disease Models, Animal<br/>Down-Regulation<br/>Enzyme Activation--drug effects<br/>Female<br/>Hepatocyte Growth Factor--metabolism<br/>Humans<br/>Macaca fascicularis<br/>Male<br/>Mice<br/>Neoplasms--drug therapy<br/>Phosphorylation<br/>Protein Transport<br/>Proteolysis<br/>Proto-Oncogene Proteins c-met--antagonists & inhibitors<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays