TY - GEN AU - Pavlidis,Polychronis AU - Ansari,Azhar AU - Duley,John AU - Oancea,Iulia AU - Florin,Timothy TI - Splitting a therapeutic dose of thioguanine may avoid liver toxicity and be an efficacious treatment for severe inflammatory bowel disease: a 2-center observational cohort study SN - 1536-4844 PY - 2015///0716 KW - Adult KW - Aged KW - Antimetabolites, Antineoplastic KW - therapeutic use KW - Chemical and Drug Induced Liver Injury KW - drug therapy KW - Cohort Studies KW - Dose-Response Relationship, Drug KW - Female KW - Follow-Up Studies KW - Humans KW - Hyperplasia KW - Inflammatory Bowel Diseases KW - Liver KW - drug effects KW - Male KW - Middle Aged KW - Prognosis KW - Severity of Illness Index KW - Thioguanine KW - Young Adult N1 - Publication Type: Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1097/MIB.0000000000000206 ER -