Ni, Xiao-Rong <br/><br/>
High concentration of insulin promotes apoptosis of primary cultured rat ovarian granulosa cells via its increase in extracellular HMGB1.  [electronic resource] 

 -  Reproductive sciences (Thousand Oaks, Calif.)  Mar 2015 
 - 271-7 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1933-7205 
<br/><br/><label>Standard No.: </label>10.1177/1933719114549852  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Case-Control Studies<br/>Cells, Cultured<br/>Dose-Response Relationship, Drug<br/>Female<br/>Granulosa Cells--drug effects<br/>HMGB1 Protein--blood<br/>Humans<br/>Insulin--toxicity<br/>Insulin Resistance<br/>Polycystic Ovary Syndrome--blood<br/>RNA Interference<br/>Rats, Sprague-Dawley<br/>Signal Transduction--drug effects<br/>Time Factors<br/>Transfection<br/>Up-Regulation