Hudecek, Michael

The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity. [electronic resource] - Cancer immunology research Feb 2015 - 125-35 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2326-6074

10.1158/2326-6066.CIR-14-0127 doi


Animals
Antigens, CD19--immunology
Burkitt Lymphoma--immunology
Cell Death--immunology
Cell Line, Tumor
Cytotoxicity, Immunologic
Genetic Engineering--methods
Genetic Vectors
Humans
Immunoglobulin G--immunology
Immunophenotyping--methods
Immunotherapy, Adoptive--methods
Lentivirus--genetics
Lung--immunology
Lymphocyte Activation--immunology
Mice, Inbred NOD
Mice, SCID
Protein Structure, Tertiary
Receptors, Antigen, T-Cell--immunology
Recombinant Fusion Proteins--immunology
Signal Transduction--immunology
Structure-Activity Relationship
T-Lymphocytes--immunology
Xenograft Model Antitumor Assays